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IMSTAR benefits from extensive expertise in the field of genotoxicity, through its active participation in European projects within the REACH program such as COMICS (automated and standardized Comets assays) and New Generis (Micronuclei) and its collaboration with ECVAM (European Centre for the Validation of Alternative Methods). Pathfinder™ systems are versatile, from research tools to fully automated high-throughput platforms for compound screening, with a distinguished clientele including Laboratoires Servier (Micronuclei testing) and L’Oréal (Comet assay).
The Pathfinder™ system, complete with our Comet applied software module, allows fully automated comet and comet head detection, as well as automated quantification of the parameters of interest (total fluorescence, Head vs Tail fluorescence, Olive moment, Extent moment, etc). The Comet module automatically takes into account the diffusion around the head to provide accurate data.
The Pathfinder™ complete with µN applied software module enables fully automated capture, detection and quantitative analysis of nuclei and micronuclei, as well as metaphases and apoptotic cells, in bright field or in fluorescence.
IMSTAR has developed the Mitodex module for fully automated:
From fully automated large scale chromosome translocations, deletions or amplification in fluorescence to presentation of metaphases to the user for assisted chromomsome aberrations scoring, IMSTAR has developed a broad range of flexible and user-oriented applications for Chromosome Aberration Scoring. In conjunction with Accell SFD robotics, metaphases can be automatically presented to the user one after the other for blind experiments for expert scoring using clickable labels for each aberration type, enabling further validation and data management. All features, labels, layouts and data locking are configurable and tailored according to client specifications.
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IMSTAR S.A.
60 Rue Notre Dame-des-Champs
75006 Paris, France
Tel: +33 (0) 1 42 34 93 70
Fax: +33 (0)1 46 34 51 57
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