Imaging systems usually fall in one of the two categories:
- Dedicated systems or general imaging toolboxes. These systems are highly specialised and very rigid and useless if user’s needs do not exactly match their narrow specification.
- Adaptable systems based on a programming environment. It is of no interest to the laboratories which do not have specialists in both programming and imaging.
Pathfinder position relative to these two classes?
First, every IMSTAR product is a turn–key system which does not require any programming skills from the user to be fully exploited. Second, our acquisition / processing / analysis of individual images correspond to the modern imaging state–of–the art. Third, our advanced experience with various research problematics enables us to adapt our products to client’s samples and reagents. And finally, IMSTAR products include some important features seldom seen among image processing systems on the market.
Pathfinder™ is an image cytometer based system offering a full solution from samples capture to quantitative results. The whole system consists of a motorized microscope, a camera and optionally high throughput devices, all managed by a single software.
3 Pathfinder systems for 3 domains of application
Dedicated to quantitative analysis in pathology studies, the MorphoScan product allows automated screening of up to 200 slides per run, on cell smear, in situ tissue section or Tissue Micro Array, according to Histologist/Pathologist expert settings. It includes modules for the most commonly used cancer diagnosis tests (cancer, brain, breast, prostate, lung and bladder) and karyotype studies.
Dedicated to High-Throughput High-Content testing to assess in vitro/in vivo genotoxicity or DNA damage for food, chemicals, cosmetic and pharmaceutic testing and product development in accordance with OECD International Guidelines . The ScreenTox product includes dedicated modules for fully automated scoring of Micro Nucleus test, Comet Assay, Mitotic index and Chromosome Aberrations test, on different formats of patterned slides, 96 wells plates/films and cell-arrays.
Dedicated to High-Throughput, High-Content Screening (HCS) the CellScan Life Sciences product provides a wide range of automated analytical solutions (instrument and comprehensive, specific software modules) for a range of automated multi-dimension analysis in controlled environment of cellular assays, multiplex phenotype screening, functional genomic signature (Cell/Lab-on-chip) for use in Life Sciences research, new biomarkers, drug development and large scale studies for Pharmaceutical, Biotech, Cosmetic and Food industries.
The complete range of Pathfinder™ products provides IMSTAR customers with unyielding capabilities in cell and tissue screening technology. Our High Throughput, High Content imaging solutions enable accurate, quantitative detection and analysis at an incredible speed.
Unlike other systems, the Pathfinder™ Image Cytometer can handle any type of sample or sample holder (regular multi-well slides, 96 to 384 well-plates, Petri dishes, multi-well slides…) as well as any type of preparation: fixed or live cell-based assays, tissues, micro-arrays, Tissue Micro Arrays…
Based on a patented IDB concept, Pathfinder™ applied or customized imaging platforms provide a way to keep the links between single cells and all its related parameters at all the stages of the analysis (i.e. image window, image mosaic, table of results, histograms, scatterplots). Those links are interactive, and the user can, at all stages of the analysis, select exactly the desired subset.
Facility of the system performance evaluation and validation by an expert
No programming skills required for deployment and use